ABSTRACT
Objective: To report a case of Multiple myeloma (MM) in mandible with paraesthesia. Material and Methods: The present case report highlights the occurrence of a swelling in the left posterior mandibular region in a 70-year old female patient and draws attention to the first clinical sign of a widespread systemic disease manifesting in the head and neck region. Results: The initial presumptive diagnosis was invalidated by the histopathological examination and other diagnostic tests that revealed the features characteristic for MM. Conclusion: Being a rare disease, MM should be kept on forefront of differential diagnosis for jaw lesions in a geriatric patient with paraesthesia. (AU)
Objetivo: Relatar um caso de mieloma múltiplo (MM) na mandíbula com parestesia. Material e Métodos: O relato de caso descreve a ocorrência de um inchaço na região mandibular posterior esquerda em uma paciente de 70 anos e chama a atenção para o primeiro sinal clínico de uma doença sistêmica disseminada que se manifesta na região da cabeça e pescoço. Resultados: O diagnóstico presuntivo inicial foi invalidado pelo exame histopatológico e outros testes diagnósticos que confirmaram as características do MM. Conclusão: Sendo uma doença rara, o MM deve ser considerado como uma primeira alternativa de diagnóstico diferencial de lesões mandibulares em pacientes geriátricos com parestesia. (AU)
Subject(s)
Humans , Aged , Paresthesia , Mandible , Multiple MyelomaABSTRACT
Background: Coronary Artery Disease (CAD) is the major cause of morbidity and mortality burden in the world. Young patients with CAD are specific subset of population requiring attention. A variety of possible contributing factors that include substance abuse, coronary artery anomalies, hypercoagulablestate, oral contraceptive use in young women have been implicated for the pathogenesis of myocardial infarction. The purpose of this study is to collect data of young patients presenting with AMI so that it would be helpful in future for better management in this particular group of patients. Aim of the present investigation was to study clinical profile of acute myocardial infarction in young patients 18-45 years of age and to study the incidence of various risk factors in young patients with myocardial infarction. Methods: The study was conducted in Department of medicine of Santosh medical college & hospital. Study was conducted on 50 cases of acute myocardial infarction if they satisfied the following selection criteria after getting formal consent and ethical clearance. Results: In our study, we have examined patients of myocardial infarction who are aged between 18-45 yrs. and other eligibility criteria for the assessment of modifiable and non-modifiable risk factors in Ghaziabad area. The ratio of male to female sex ratio in our study is 5.25:1 and 64% of the patients in present study had anterior wall MI while 24% had inferior wall MI and 12% had antero-septal wall MI. Conclusions: Mean age of study group is 36.24 ±4.32 years. The maximum number of patients was in 35-40 years of age. Youngest patient was 25 years old male. The incidence of acute myocardial infarction is increasing in younger age group.